| 释义 |
flunitrazepam, n. Pharmacol.
Brit. |ˌfluːnʌɪˈtreɪzɪpam|, |ˌfluːnʌɪˈtrazɪpam|, U.S. |ˌflunaɪˈtræzəˌpæm|
[‹ flu- (in fluoro- comb. form) + nitro- comb. form + -azepam comb. form.]
A short-acting benzodiazepine derivative with relatively long-lasting sedative effects, used as a hypnotic and as a premedication for anaesthesia; 5-(2-fluorophenyl)-1,3-dihydro-1-methyl-7-nitro-2H-1,4-benzodiazepin-2-one, C16H12FN3O3.
A proprietary name for this drug is Rohypnol n.
1973S. Afr. Med. Jrnl. 47 787 Preliminary animal experiments and clinical trials with a new benzodiazepine derivative, flunitrazepam, indicated a strong hypnotic action when given as an oral medication. 1984Jrnl. Neurochem. 43 272 When subjected to ultraviolet light flunitrazepam could be irreversibly attached to brain membrane preparations. 1997Des Moines (Iowa) Reg. (Nexis) 26 Mar. 4 Flunitrazepam, which is odorless and colorless, has been used to make women susceptible to sexual assault. Slipped into a victim's drink, it causes drowsiness and confusion and can result in blackouts lasting several hours. 2000Amer. Family Physician (Nexis) 62 2520 Flunitrazepam is banned in the United States but available as a sedative/tranquilizer in Europe and other parts of the world. |
