| Acronym | Definition |
|---|
| SPEAK | Speaking Proficiency English Assessment Kit (Educational Testing Service) |
| SPEAK | Supporting and Promoting Ethics for the Animal Kingdom (est. 1990) |
| SPEAK | Students Promoting Environmental Action in Knoxville (student group; University of Tennessee; Knoxville, TN) |
| SPEAK | Students Promoting Empowerment and Knowledge (est. 1998; Columbia University; New York) |
| SPEAK | Support Public Education-Act for Kids (Alberta, Canada) |
| SPEAK | Suicide Prevention Education Awareness for Kids |
