| Acronym | Definition |
|---|
| MSPO | Master of Science in Prosthetics and Orthotics (various universities) |
| MSPO | Maine State Planning Office (also seen as MESPO) |
| MSPO | Middelbaar Sociaal Pedagogisch Onderwijs (Dutch: Secondary Social Pedagogic Education) |
| MSPO | Miedzynarodowy Salon Przemyslu Obronnego (Polish: International Defense Industry Salon) |
| MSPO | Monotonic Semantic Path Ordering (computing) |
| MSPO | Mission Services Program Office (US NASA) |
| MSPO | Management Systems Program Office |
