| Acronym | Definition |
|---|
| IRSM | Irish Republican Socialist Movement |
| IRSM | Institute of Rock Structure and Mechanics (Academy of Sciences of the Czech Republic) |
| IRSM | Inline Real-Time Stream Monitoring |
| IRSM | Institute for Reconstructive Sciences in Medicine (Edmonton, AB, Canada) |
| IRSM | Iraq Reconstruction Service Medal (UK) |
| IRSM | International Revolutionary Solidarity Movement (anarchist group) |
| IRSM | Interface Requirements Specification Manual |
| IRSM | International Risk and Security Management Pty Ltd |
