| Acronym | Definition |
|---|
| IRSD | Information Resources and Services Division |
| IRSD | Index of Relative Socioeconomic Disadvantage (Department of Health; New South Wales, Australia) |
| IRSD | Immune-Related Stable Disease (cancer) |
| IRSD | Institut Royal Supérieur de Défense (French: Royal Defence College, Belgium) |
| IRSD | Image Receptor Support Device |
| IRSD | Independent Roller Shutters & Doors Ltd (Ireland) |
| IRSD | Institute on Race and Social Division (Boston University) |
| IRSD | Internal Revenue Service Document |
